Glyxambi (empagliflozin and linagliptin) Medicine - Uses, Precautions, Indications

What is Glyxambi?

Glyxambi (empagliflozin and linagliptin) is a combination of an inhibitor of the sodium-glucose co-transporter (SGLT2) and an inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme as an adjunct to diet and exercise to improve glycemic control.

What are the side effects of Glyxambi?

Common side effects of Glyxambi include:

• urinary tract infection

• Common cold symptoms

• Upper respiratory tract infection

• Genital Yeast Infection

• Increased urination

• Joint pain

• Nausea

• runny or stuffy nose

• Diarrhea

• cough

• Elevated blood cholesterol or fat

• Diarrhea

Glyxambi Dosage

The recommended dose of Glyxambi is 10 mg empagliflozin/5 mg linagliptin, taken once daily in the morning, with or without food. In patients who tolerate Glyxambi, the dose may be increased to 25 mg empagliflozin/5 mg linagliptin once daily.

Do drugs, substances, or supplements interact with Glyxambi?

Glyxambi during pregnancy and lactation

During pregnancy, Glyxambi should be taken only when prescribed. Consult your doctor before breastfeeding.

Additional Information

Our Glyxambi (empagliflozin and linagliptin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side-effects and others may occur. You can report side effects to the FDA at 1-800-FDA-1088.

Get emergency medical help if you have signs of an allergic reaction: hives, itching, crusting, or peeling skin; trouble swallowing, difficulty breathing; swelling of your face, lips, tongue, or throat.

Seek medical attention right away if you have symptoms of a serious genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness, or swelling of the genital or rectal area, fever, not feeling well. . These symptoms can get worse quickly.

• light-headedness, as if you might faint;

• severe skin reaction -- itching, blistering, cracking of the outer layer of the skin;

• pancreatitis - severe pain in your upper abdomen spreading to your back, nausea and vomiting;

• Dehydration -- dizziness, confusion, feeling very thirsty, decreased urination;

• symptoms of a bladder infection--pain or burning when urinating, blood in your urine, pelvic or back pain; either

• signs of heart failure--shortness of breath (even when lying down), swelling in your legs or feet, rapid weight gain.

Common side effects may include:

• Bladder infections; either

• Cold symptoms such as runny or stuffy nose, sneezing, sore throat.

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