What Is IDHIFA (Enasidenib)? Causes, Side Effects, Dosage

 WHAT IS IDHIFA (Enasidenib)?

IDHIFA Medicine
IDHIFA Medicine
IDHIFA is a prescription medicine used to treat people with acute myeloid leukemia (AML) with an isocitrate dehydrogenase-2 (IDH2) mutation whose disease has come back or has not improved after previous treatment(s). It is not known if IDHIFA is safe and effective in children.

IDHIFA may cause serious side effects, including:

Differentiation Syndrome. Differentiation syndrome is a condition that affects your blood cells which may be life-threatening or lead to death if not treated. Differentiation syndrome has happened within 1 day and up to 5 months after starting IDHIFA. Check the following symptoms below.

  • ·         fever
  • ·         cough
  • ·         shortness of breath
  • ·         swelling of arms and legs
  • ·         fast weight gain (greater than 10 pounds within a week)
  • ·         bone pain

If you develop any of these symptoms of differentiation syndrome, your healthcare provider may start you on a medicine taken by mouth or given through a vein (intravenous) called corticosteroids and may monitor you in the hospital.

How Should I take IDHIFA?

Take IDHIFA Medicine 1 time a day at the same time each day. Swallow IDHIFA tablets whole with 8 ounces (one cup) of water. If you miss a dose of IDHIFA or vomit after taking a dose of IDHIFA, take the dose of IDHIFA as soon as possible on the same day.

Your healthcare provider should do blood tests to check your blood counts before you start IDHIFA treatment and at a minimum of every 2 weeks for at least the first 3 months during treatment to check for side effects

The Most Common Side Effects of IDHIFA include:

  • ·         nausea
  • ·         vomiting
  • ·         diarrhea
  • ·         jaundice
  • ·         decreased appetite

Tell your healthcare provider if you have any changes to the color of your skin or the whites of your eyes.

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