Lonsurf (Trifluridine Tipiracil) | Named Patient Program India

 In a clinical trial, half of patients with metastatic colon or rectal cancer treated with LONSURF® (trifluridine and tipiracil) Tablets were still alive at 7.1 months and half of patients who received placebo were still alive at 5.3 months were alive. Worsening of disease or death occurred in 88% of patients treated with LONSURF and 94% of patients receiving placebo.

In the clinical trial, half of the patients with metastatic colon cancer treated with LONSURF were still alive at 5.7 months and half of the patients who received placebo were still alive at 3.6 months. Worsening of disease or death occurred in 85% of patients treated with LONSURF and 92% of patients receiving placebo.

 

Signs and important safety information

LONSURF is a prescription medicine used to treat adults

• Colorectal cancer that has spread to other parts of the body and has been previously treated or cannot receive certain chemotherapy drugs.

• A type of stomach cancer called gastric cancer, including cancer of the gastroesophageal junction that has spread to other parts of the body and who have been previously treated or cannot receive certain chemotherapy drugs.

Important Security Information

Serious side effects of LONSURF can occur, including:

• Low blood counts. Low blood count is common with LONSURF and can sometimes be serious and life-threatening. Low white blood cells can make you more likely to get serious infections that can lead to death. Your healthcare provider should perform blood tests before you receive LONSURF, on Day 15 during treatment with LONSURF, and as needed to check your blood cell count. Your healthcare provider may lower your dose of Lonsurf or stop Lonsurf if you have low white blood cell or platelet counts.

Before taking LONSURF, tell your healthcare provider about all of your medical conditions, including if you:

• have kidney or liver problems

• Are pregnant or planning to become pregnant. LONSURF may harm your unborn baby.

• Women may become pregnant: Your healthcare provider will confirm your pregnancy status before starting treatment with Lonsurf. You must use effective birth control during and for 6 months after your last dose of treatment with LONSURF. Tell your healthcare provider right away if you become pregnant.

• Men, during treatment and for 3 months after the last dose of LONSURF, you should use a condom during sex with female partners who are capable of becoming pregnant. Tell your healthcare provider right away if your partner becomes pregnant while taking Lonsurf.

• Are breast-feeding or planning to breast-feed. It is not known whether Lonsurf passes into your breast milk.

Tell your healthcare provider about all prescription and over-the-counter medicines, vitamins, and herbal supplements you take.

The most common side effects with Lonsurf include fatigue (tiredness, weakness), nausea, loss of appetite, diarrhea, vomiting, abdominal pain, and fever.

These are not all the possible side effects of Lonsurf. For more information, ask your healthcare provider. You can call your doctor for medical consultation about the side effects. You can Imported Medicines In India through the Named Patient Program India.