Causes of Ulcerative Colitis | Named Patient Medicine

Autoimmune Condition

The immune system is the body's defense against infection. Many experts believe that ulcerative colitis is an autoimmune condition (when the immune system mistakenly attacks healthy tissue).The immune system usually fights infection by releasing white blood cells into the blood to destroy the cause of the infection. This results in swelling and redness (swelling) of the body tissues in the infected area. In ulcerative colitis, a leading theory is that the immune system mistakes the "friendly bacteria" in the colon, which aid digestion, as a harmful infection, leading to inflammation of the colon and rectum.

Alternatively, some researchers believe that a viral or bacterial infection triggers the immune system, but for some reason it does not "shut off" after the infection has passed and cause inflammation.

It has also been suggested that there is no infection involved and that the immune system may malfunction on its own, or that there is an imbalance between good and bad bacteria within the bowel. AlleviareIndia a pharma consulting company helps patients and hospitals to procur named patient medicine. 

Genetics

It also seems that inherited genes are a factor in the development of ulcerative colitis. Studies have shown that more than 1 in 4 people with ulcerative colitis has a family history of the condition. Levels of ulcerative colitis are also very high in some ethnic groups, further suggesting that genetics is a factor. Researchers have identified several genes that make people more likely to develop ulcerative colitis. It is believed that many of these genes play a role in the immune system. Alleviare India provides consultation to patients in getting access to speciality drugs which are not available or approved in the country and make it possible via named patient program.

Where and how you live affects your chances of developing ulcerative colitis, which suggests that environmental factors are important. For example, the condition is more common in urban areas of Western Europe and northern parts of the Americas. Various environmental factors associated with ulcerative colitis have been studied, including air pollution, medication, and certain diets. Although no causative factors have yet been identified, countries with better sanitation have higher populations of people with the condition. This suggests that a reduction in exposure to bacteria may be an important factor.